Marital satisfaction : A predictor of post-partum depression

Abstract Post-Partum Depression (PPD) is the most common mental health disorder that has raised major public health concerns. Post-partum depression is related to various adverse health outcomes for mothers and children. Studies from lower and middle-income countries suggest up to 25% of pregnant women experience symptoms of common mental health disorders, including depression. Post-partum depression adversely affects a mother’s mental health, quality of life, and interactions with their partner, infant, and relatives and can predispose her to subsequent depression. Factors such as prenatal depression and stressful life events like marital dysfunction or conflict are gaining researchers’ attention, with additional focus on effects on the infant. It is crucial to comprehend how social support and marital satisfaction affect the prevention and treatment of post-partum depression

Unsteady Axisymmetric Rotational Flow of Dusty Elastico Viscous Liquid

This paper reports the flow of elastico-viscous liquid embedded with particles in an oscillating cylinder. Explicit expressions are obtained for the velocities of liquid and dust particles by the technique of Laplace transforms. Numerical computations of the velocity fields are carried out for different values of mass concentration and relaxation time of the dust particles and varying elastic elements in the liquid

Selection of stable housekeeping genes for gene expression studies in different varieties of black pepper (Piper nigrum L.)

Real Time quantitative PCR (RT-qPCR) is a widely used technique to study the transcript level modulation of genes during developmental stages of crop plants as well as in stress responses. Suitable reference genes have not been validated in many plants including black pepper. In this study, expression stability of six commonly used housekeeping genes viz., actin, ?-tubulin, elongation factor, initiation factor, ubiquitin and glyceraldehyde 3- phosphate dehydrogenase were evaluated by RT-qPCR during the growth of the black pepper inflorescence of varieties viz., Panniyur 1, Karimunda and Thekken. The results were analyzed using geNorm and Normfinder statistical algorithms. Stable reference gene is critical for the accurate normalization of target gene data in RT-qPCR. In this study actin, elongation factor and initiation factor were identified as the most stable housekeeping gene in different black pepper varieties viz., Thekken, Panniyur 1 and Karimunda respectively. Actin in combination with GAPDH and elongation factor were obtained as optimal reference genes for Thekken. It is the first report on identification of stable housekeeping gene in different varieties of black pepper and can aid in expression studies in black pepper for yield improvement. The study will aid in normalization of gene expression studies in different varieties of black pepper

Seroprevalence of transfusion transmitted infections in voluntary and replacement blood donors in a tertiary care hospital blood bank of Anantapur, Andhra Pradesh, India: 5 years retrospective study

Background: Critical part of transfusion is effective screening of TTI, to reduce the risk of transmission is as safe as possible. The present study has undertaken to focus on seroprevalence of TTIs among both voluntary and replacement donors and also to project epidemiological data of TTIs in this community.Methods: This is a retrospective study conducted from January 2014 to December 2018. All blood samples collected from donors were screened for HIV, HBV, HCV, Syphilis and malaria according to blood bank policy. Before drawing blood, donors were asked to fill pre structured Blood bank questionnaire and consent form.Results: In this present 5-year study, total number of blood donor population was 54937, among them voluntary donors were 33891 and replacement donors were 21046. Out of 33891 voluntary donors, 33486(98.8%) were males and remaining 405(1.19%) were females. All replacement donors (21046) were males. The seroprevalence of HBV was highest, 1.82% (1003/54937) followed by HCV 0.31% (175/54937) in all the donors. The seropositivity for HIV is 0.23% (129/54937), for syphilis 0.04% (24/54937) and for malaria 0.01% (6/54937).Conclusions: National blood transfusion policy should be strengthening the standards and quality of screening across the country. For blood screening, resources and appropriate screening assays must be available at all health centres

Mortality profile and incidence of deaths due to neonatal sepsis in an urban tertiary care center in South India: A retrospective study

Background: The neonatal mortality rate is a key outcome indicator for newborn care and directly reflects prenatal, intrapartum, and neonatal care. Objective: Primary objective was to assess the neonatal mortality profile, incidence of neonatal sepsis among total neonatal deaths and pattern of antimicrobial resistance. Methodology: This was a retrospective descriptive study done at a tertiary care center. All neonatal deaths from January 2014 to December 2014 were reviewed, and primary causes of mortality, incidence of sepsis among neonatal deaths and pattern of antimicrobial resistance were analyzed. Results: Common causes of neonatal mortality were sepsis, respiratory distress syndrome, congenital malformations, asphyxia, extreme preterm, meconium aspiration syndrome. Case fatality rate was high in extreme preterm neonates (82%), followed by respiratory distress syndrome (29%), congenital malformations (29%), sepsis (25%), asphyxia (25%). In our study incidence of neonatal sepsis among total neonatal deaths was about 20.5%. Staphylococcus aureus (60%) and Klebsiella pneumoniae (23%) were predominant organisms. Highest case fatality rate was associated with K. pneumoniae sepsis about 60%, followed by Escherichia coli sepsis (54%) and Acinetobacter sepsis (50%). Multidrug resistance is an emerging problem, especially in Acinetobacter sepsis. Conclusion: Sepsis still remains the leading cause of death in developing countries. S. aureus was the most common predominant organism; of this, two-thirds were methicillin-resistant S. aureus. About 90% of K. pneumoniae were resistant to extended-spectrum cephalosporins. Multidrug resistance is an emerging problem, especially in Acinetobacter sepsis